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ARSENITE AND INSULIN EXHIBIT OPPOSING EFFECTS ON EPIDERMAL GROWTH FACTOR RECEPTOR AND KERATINOCYTE PROLIFERATIVE POTENTIAL

Previous work has suggested that arsenic exposure contributes to skin carcinogenesis by preserving the proliferative potential of human epidermal keratinocytes, thereby slowing the exit of putative target stem cells into the differentiation pathway. To find a molecular basis for this action, present...

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Autori principali: Patterson, Timothy J., Rice, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950287/
https://ncbi.nlm.nih.gov/pubmed/17400267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.02.003
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