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Organosilicon-Containing Thiazole Derivatives as Potential Lipoxygenase Inhibitors and Anti-Inflammatory Agents

A number of trimethylsiloxyalkyl and trialkylsilylalkyl thiazole derivatives have been evaluated for their anti-inflammatory activity, lipoxygenase inhibiting properties, and cytotoxicity. The investigated compounds have been found to protect in vivo against carrageenin-induced edema, especially 3-(...

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Detalhes bibliográficos
Main Authors: Geronikaki, Athina, Hadjipavlou-Litina, Dimitra, Zablotskaya, Alla, Segal, Izolda
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950228/
https://ncbi.nlm.nih.gov/pubmed/18256725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/92145
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