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Suppression of type I collagen gene expression by prostaglandins in fibroblasts is mediated at the transcriptional level.

BACKGROUND: Tissues undergoing a chronic inflammatory process, such as the synovium in rheumatoid arthritis, are characterized by the infiltration of lymphocytes of different subsets and activation of monocyte/macrophages. Interleukin-1 (IL-1), a monocyte/ macrophage product that stimulates synovial...

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Bibliografische gegevens
Hoofdauteurs: Riquet, F. B., Lai, W. F., Birkhead, J. R., Suen, L. F., Karsenty, G., Goldring, M. B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949972/
https://ncbi.nlm.nih.gov/pubmed/11055589
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