VEINCTR-N, an immunogenic epitope of Fas (CD95/Apo-I), and soluble Fas enhance T-cell apoptosis in vitro. II. Functional analysis and possible implications in HIV-1 disease.

BACKGROUND: Recent studies indicate that soluble Fas (sFas) may modulate T-cell apoptosis, since it inhibits Fas-ligand (Fas-L)-mediated cytotoxicity in vitro. Here, we explored whether the soluble receptor and its major immunogenic domain, namely VEINCTR-N, interfered with apoptosis of T cells from...

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Main Authors: Silvestris, F., Cafforio, P., Tucci, M., Del Prete, A., Dammacco, F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2000
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949964/
https://ncbi.nlm.nih.gov/pubmed/10972087
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