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On State-Space Reduction in Multi-Strain Pathogen Models, with an Application to Antigenic Drift in Influenza A

Many pathogens exist in phenotypically distinct strains that interact with each other through competition for hosts. General models that describe such multi-strain systems are extremely difficult to analyze because their state spaces are enormously large. Reduced models have been proposed, but so fa...

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Hlavní autoři: Kryazhimskiy, Sergey, Dieckmann, Ulf, Levin, Simon A, Dushoff, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949840/
https://ncbi.nlm.nih.gov/pubmed/17708677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030159
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