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Gene duplication, modularity and adaptation in the evolution of the aflatoxin gene cluster

BACKGROUND: The biosynthesis of aflatoxin (AF) involves over 20 enzymatic reactions in a complex polyketide pathway that converts acetate and malonate to the intermediates sterigmatocystin (ST) and O-methylsterigmatocystin (OMST), the respective penultimate and ultimate precursors of AF. Although th...

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Bibliografiske detaljer
Main Authors: Carbone, Ignazio, Ramirez-Prado, Jorge H, Jakobek, Judy L, Horn, Bruce W
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949824/
https://ncbi.nlm.nih.gov/pubmed/17620135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-111
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