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Purified mouse dopamine neurons thrive and function after transplantation into brain but require novel glial factors for survival in culture

Cell replacement therapy in Parkinson's disease depends on a reliable source of purified dopamine (DA) neurons (PDN) and the identification of factors relevant to their survival. Our goal was to genetically tag and purify by flow cytometry embryonic midbrain DA neurons from a transgenic mouse l...

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Detalhes bibliográficos
Main Authors: Donaldson, A.E., Marshall, C.E., Yang, Ming, Suon, S., Iacovitti, Lorraine
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949425/
https://ncbi.nlm.nih.gov/pubmed/16024255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2005.06.004
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