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Plasma Membrane and Nuclear Localization of G Protein–coupled Receptor Kinase 6A

G protein–coupled receptor (GPCR) kinases (GRKs) specifically phosphorylate agonist-occupied GPCRs at the inner surface of the plasma membrane (PM), leading to receptor desensitization. Here we show that the C-terminal 30 amino acids of GRK6A contain multiple elements that either promote or inhibit...

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Detalhes bibliográficos
Main Authors: Jiang, Xiaoshan, Benovic, Jeffrey L., Wedegaertner, Philip B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949383/
https://ncbi.nlm.nih.gov/pubmed/17538017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-01-0013
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