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Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation

When activated by proinflammatory stimuli, microglia release substantial levels of glutamate, and mounting evidence suggests this contributes to neuronal damage during neuroinflammation. Prior studies indicated a role for the Xc exchange system, an amino acid transporter that antiports glutamate for...

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Detalhes bibliográficos
Main Authors: Barger, Steven W., Goodwin, Mary E., Porter, Mandy M., Beggs, Marjorie L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949347/
https://ncbi.nlm.nih.gov/pubmed/17403030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.04487.x
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