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Characterizing the role of Hsp90 in production of heat shock proteins in motor neurons reveals a suppressive effect of wild-type Hsf1

Induction of heat shock proteins (Hsps) is under investigation as treatment for neurodegenerative disorders, yet many types of neurons, including motor neurons that degenerate in amyotrophic lateral sclerosis (ALS), have a high threshold for activation of the major transcription factor mediating str...

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Detalhes bibliográficos
Main Authors: Taylor, David M., Tradewell, Miranda L., Minotti, Sandra, Durham, Heather D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Stress Society International 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949336/
https://ncbi.nlm.nih.gov/pubmed/17688194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-254R.1
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