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Role of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1
Spinocerebellar ataxia-1 (SCA1) is caused by the expansion of a polyglutamine repeats within the disease protein, ataxin-1. The mutant ataxin-1 precipitates as large intranuclear aggregates in the affected neurons. These aggregates may protect neurons from mutant protein and/or trigger neuronal dege...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1949022/ https://ncbi.nlm.nih.gov/pubmed/17442486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.04.005 |
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