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Role of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1

Spinocerebellar ataxia-1 (SCA1) is caused by the expansion of a polyglutamine repeats within the disease protein, ataxin-1. The mutant ataxin-1 precipitates as large intranuclear aggregates in the affected neurons. These aggregates may protect neurons from mutant protein and/or trigger neuronal dege...

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Detalhes bibliográficos
Main Authors: Vig, P.J.S., Wei, J., Shao, Q., Hebert, M.D., Subramony, S.H., Sutton, L.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949022/
https://ncbi.nlm.nih.gov/pubmed/17442486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.04.005
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