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Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma

Protein arginine methyltransferase PRMT5 interacts with human SWI/SNF complexes and methylates histones H3R8 and H4R3. To elucidate the role of PRMT5 in human cancer, we analyzed PRMT5 expression in normal human B lymphocytes and a panel of lymphoid cancer cell lines as well as mantle cell lymphoma...

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Detalhes bibliográficos
Main Authors: Pal, Sharmistha, Baiocchi, Robert A, Byrd, John C, Grever, Michael R, Jacob, Samson T, Sif, Saïd
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949000/
https://ncbi.nlm.nih.gov/pubmed/17627275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601794
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