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Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na(+) channels

Av3 is a short peptide toxin from the sea anemone Anemonia viridis shown to be active on crustaceans and inactive on mammals. It inhibits inactivation of Na(v)s (voltage-gated Na(+) channels) like the structurally dissimilar scorpion α-toxins and type I sea anemone toxins that bind to receptor site-...

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Autori principali: Moran, Yehu, Kahn, Roy, Cohen, Lior, Gur, Maya, Karbat, Izhar, Gordon, Dalia, Gurevitz, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948988/
https://ncbi.nlm.nih.gov/pubmed/17492942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070233
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