Co-planar 3,3′,4,4′,5-pentachlorinated biphenyl and non-co-planar 2,2′,4,6,6′-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor α to aryl hydrocarbon receptor target genes

In the present study we examined the ability of 3,3′,4,4′,5-pentachlorinated biphenyl [PCB126 (polychlorinated biphenyl 126)], a prototypical AHR (aryl hydrocarbon receptor) agonist, and 2,2′,4,6,6′-PCB (PCB104), which does not activate AHR, to induce the recruitment of ERα (oestrogen receptor α) to...

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Detalhes bibliográficos
Main Authors: Matthews, Jason, Wihlén, Björn, Heldring, Nina, MacPherson, Laura, Helguero, Luisa, Treuter, Eckardt, Haldosén, Lars-Arne, Gustafsson, Jan-Åke
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948966/
https://ncbi.nlm.nih.gov/pubmed/17511620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070585
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