Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells

HTLV-1 (human T-cell leukaemia virus type 1) is the causative agent for ATL (adult T-cell leukaemia). HTLV-1 Tax can activate the PI3K (phosphoinositide 3-kinase)/Akt signalling pathway, which is responsible for survival of HTLV-1-infected T-cells. HIFs (hypoxia-inducible factors) are transcriptiona...

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Bibliographische Detailangaben
Hauptverfasser: Tomita, Mariko, Semenza, Gregg L., Michiels, Canine, Matsuda, Takehiro, Uchihara, Jun-Nosuke, Okudaira, Taeko, Tanaka, Yuetsu, Taira, Naoya, Ohshiro, Kazuiku, Mori, Naoki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948965/
https://ncbi.nlm.nih.gov/pubmed/17576198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070286
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