IL-8 secreted in a macrophage migration-inhibitory factor- and CD74-dependent manner regulates B cell chronic lymphocytic leukemia survival

Chronic lymphocytic leukemia (CLL) is a malignant disease of small mature lymphocytes. Previous studies have shown that CLL B lymphocytes express relatively large amounts of CD74 mRNA relative to normal B cells. In the present study, we analyzed the molecular mechanism regulated by CD74 in B-CLL cel...

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Autors principals: Binsky, Inbal, Haran, Michal, Starlets, Diana, Gore, Yael, Lantner, Frida, Harpaz, Nurit, Leng, Lin, Goldenberg, David M., Shvidel, Lev, Berrebi, Alain, Bucala, Richard, Shachar, Idit
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948950/
https://ncbi.nlm.nih.gov/pubmed/17686984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701553104
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