TAp63 Regulates VLA-4 Expression and Chronic Lymphocytic Leukemia Cell Migration to the Bone Marrow in a CD74-Dependent Manner

The hallmark of chronic lymphocytic leukemia (CLL) is the relentless accumulation of mature lymphocytes, mostly due to their decreased apoptosis. CD74 was recently shown to serve as a survival receptor on CLL cells. In this study, we show that stimulation of CD74 with its natural ligand, migration i...

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Main Authors: Binsky, Inbal, Lantner, Frida, Grabovsky, Valentin, Harpaz, Nurit, Shvidel, Lev, Berrebi, Alain, Goldenberg, David M., Leng, Lin, Bucala, Richard, Alon, Ronen, Haran, Michal, Shachar, Idit
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129539/
https://ncbi.nlm.nih.gov/pubmed/20357260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904149
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