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Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels
Cells contain numerous enzymes that use molecular oxygen for their reactions. Often, their active sites are buried deeply inside the protein, which raises the question whether there are specific access channels guiding oxygen to the site of catalysis. Choosing 12/15-lipoxygenase as a typical example...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948941/ https://ncbi.nlm.nih.gov/pubmed/17675410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702401104 |
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