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A Dipolar Cycloaddition Approach Toward the Kopsifoline Alkaloid Framework

Using a metal-catalyzed domino reaction as the key step, the heterocyclic skeleton of the kopsifoline alkaloid family was constructed by a 1,3-dipolar cycloaddition of a carbonyl ylide dipole derived from a Rh(II)-catalyzed reaction of a diazo ketoester across the indole π-bond. Ring opening of the...

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Detalhes bibliográficos
Main Authors: Hong, Xuechuan, France, Stefan, Padwa, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948834/
https://ncbi.nlm.nih.gov/pubmed/17710185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.01.064
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