Mre11 and Ku Regulation of Double-Strand Break Repair by Gene Conversion and Break-Induced Replication

The yeast Mre11-Rad50-Xrs2 (MRX) and Ku complexes regulate single-strand resection at DSB double-strand breaks (DSB), a key early step in homologous recombination (HR). A prior plasmid gap repair study showed that mre11 mutations, which slow single-strand resection, reduce gene conversion tract leng...

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Main Authors: Krishna, Sanchita, Wagener, Brant M., Liu, Hui Ping, Lo, Yi-Chen, Sterk, Rosa, Petrini, John H.J., Nickoloff, Jac A.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948817/
https://ncbi.nlm.nih.gov/pubmed/17321803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.01.006
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