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Dual transcriptional activities underlie opposing effects of retinoic acid on cell survival

Transcriptional activation of the nuclear receptor RAR by retinoic acid (RA) often leads to inhibition of cell growth. However, in some tissues, RA promotes cell survival and hyperplasia, activities that are unlikely to be mediated by RAR. Here we show that, in addition to functioning through RAR, R...

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Autori principali: Schug, Thaddeus T, Berry, Daniel C., Shaw, Natacha S., Travis, Skylar N., Noy, Noa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948722/
https://ncbi.nlm.nih.gov/pubmed/17512406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.02.050
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