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Dual transcriptional activities underlie opposing effects of retinoic acid on cell survival
Transcriptional activation of the nuclear receptor RAR by retinoic acid (RA) often leads to inhibition of cell growth. However, in some tissues, RA promotes cell survival and hyperplasia, activities that are unlikely to be mediated by RAR. Here we show that, in addition to functioning through RAR, R...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948722/ https://ncbi.nlm.nih.gov/pubmed/17512406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.02.050 |
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