In situ hybridization analysis of presenilin 1 mRNA in Alzheimer disease and in lesioned rat brain
Presenilin-1 (PS-1) gene mutations are responsible for the majority of the early onset familial forms of Alzheimer disease (AD). Neither PS-1’s anatomic distribution in brain nor expression in AD have been reported. Using in situ hybridization in the rat forebrain, we show that PS-1 mRNA expression...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19487/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.14020 |
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