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Mechanism of inhibition of bovine F(1)-ATPase by resveratrol and related polyphenols

The structures of F(1)-ATPase from bovine heart mitochondria inhibited with the dietary phytopolyphenol, resveratrol, and with the related polyphenols quercetin and piceatannol have been determined at 2.3-, 2.4- and 2.7-Å resolution, respectively. The inhibitors bind to a common site in the inside s...

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Detalhes bibliográficos
Main Authors: Gledhill, Jonathan R., Montgomery, Martin G., Leslie, Andrew G. W., Walker, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948022/
https://ncbi.nlm.nih.gov/pubmed/17698806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706290104
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