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Complete suppression of viral gene expression is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheep

BACKGROUND: During malignant progression, tumor cells need to acquire novel characteristics that lead to uncontrolled growth and reduced immunogenicity. In the Bovine Leukemia Virus-induced ovine leukemia model, silencing of viral gene expression has been proposed as a mechanism leading to immune ev...

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Bibliografiske detaljer
Main Authors: Merimi, Makram, Klener, Pavel, Szynal, Maud, Cleuter, Yvette, Bagnis, Claude, Kerkhofs, Pierre, Burny, Arsène, Martiat, Philippe, Van den Broeke, Anne
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948017/
https://ncbi.nlm.nih.gov/pubmed/17645797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-51
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