Suppression of Viral Gene Expression in Bovine Leukemia Virus-Associated B-Cell Malignancy: Interplay of Epigenetic Modifications Leading to Chromatin with a Repressive Histone Code

Ovine leukemia/lymphoma resulting from bovine leukemia virus infection of sheep offers a large animal model for studying mechanisms underlying leukemogenesis. Silencing of viral information including Tax, the major contributor to the oncogenic potential of the virus, is critical if not mandatory for...

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Autores principales: Merimi, Makram, Klener, Pavel, Szynal, Maud, Cleuter, Yvette, Kerkhofs, Pierre, Burny, Arsène, Martiat, Philippe, Van den Broeke, Anne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900279/
https://ncbi.nlm.nih.gov/pubmed/17392371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02606-06
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