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Incorporation of genetic model parameters for cost-effective designs of genetic association studies using DNA pooling

BACKGROUND: Studies of association methods using DNA pooling of single nucleotide polymorphisms (SNPs) have focused primarily on the effects of "machine-error", number of replicates, and the size of the pool. We use the non-centrality parameter (NCP) for the analysis of variance test to co...

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Bibliografske podrobnosti
Main Authors: Ji, Fei, Finch, Stephen J, Haynes, Chad, Mendell, Nancy R, Gordon, Derek
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1947971/
https://ncbi.nlm.nih.gov/pubmed/17634103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-238
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