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Transcription-induced mutations: Increase in C to T mutations in the nontranscribed strand during transcription in Escherichia coli
Cytosines in single-stranded DNA deaminate to uracils at 140 times the rate for cytosines in double-stranded DNA. If resulting uracils are not replaced with cytosine, C to T mutations occur. These facts suggest that cellular processes such as transcription that create single-stranded DNA should prom...
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The National Academy of Sciences of the USA
1996
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC19468/ https://ncbi.nlm.nih.gov/pubmed/8943036 |
| टैग : |
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