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DEPLETION OF CELLULAR CHOLESTEROL INHIBITS MEMBRANE BINDING AND HIGHER-ORDER MULTIMERIZATION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GAG
Recent studies have suggested that the plasma membrane contains cholesterol-enriched microdomains known as lipid rafts. HIV-1 Gag binds raft-rich regions of the plasma membrane, and cholesterol depletion impairs HIV-1 particle production. In this study, we sought to define the block imposed by chole...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1945131/ https://ncbi.nlm.nih.gov/pubmed/17095032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.10.011 |
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