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INVESTIGATION OF THE METABOLISM OF SUBSTANCE P AT THE BLOOD-BRAIN BARRIER USING LC-MS/MS

Substance P (SP) has been associated with pain and depression as well as neurodegenerative diseases. Many of these diverse actions of SP can potentially be attributed to SP metabolites generated at the blood-brain barrier (BBB). In this study, the metabolism of SP was investigated using an in vitro...

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Détails bibliographiques
Auteurs principaux: Chappa, Arvind K., Cooper, Joshua D., Audus, Kenneth L., Lunte, Susan M.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1945052/
https://ncbi.nlm.nih.gov/pubmed/17118606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2006.10.005
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