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Expression of Q227L-Gα(s) in MCF-7 human breast cancer cells inhibits tumorigenesis

The effects of expression of mutant (Q227L)-activated Gα(s) and elevation of cAMP on mitogen-activating protein kinase (MAPK) activity and the transformed phenotype were studied in the MCF-7 human mammary epithelial cell line. Elevation of cAMP partially inhibited the epidermal growth factor-stimula...

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Detalhes bibliográficos
Main Authors: Chen, Jianghao, Bander, Jeffry A., Santore, Tara Ann, Chen, Yibang, Ram, Prahlad T., Smit, Martine J., Iyengar, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19449/
https://ncbi.nlm.nih.gov/pubmed/9482941
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