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Adenovirus-directed expression of Q227L-Gα(s) inhibits growth of established tumors of later-stage human breast cancer cells in athymic mice

Elevation of cAMP inhibits proliferation and expression of the transformed phenotype in several cell types. We studied the effects of elevation of cAMP and expression of mutant (Q227L) activated Gα(s) on the proliferation and tumorigenic capability of the later stage, metastatic estrogen-independent...

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Detalhes bibliográficos
Main Authors: Santore, Tara Ann, Chen, Yibang, Smit, Martine J., Iyengar, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122249/
https://ncbi.nlm.nih.gov/pubmed/11805301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032661999
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