CD28 co-stimulation via tumour-specific chimaeric receptors induces an incomplete activation response in Epstein–Barr virus-specific effector memory T cells

Expression of tumour antigen-specific chimaeric receptors in T lymphocytes can redirect their effector functions towards tumour cells. Integration of the signalling domains of the co-stimulatory molecule CD28 into chRec enhances antigen-specific proliferation of polyclonal human T cell populations....

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Bibliografiske detaljer
Main Authors: Altvater, B, Pscherer, S, Landmeier, S, Niggemeier, V, Juergens, H, Vormoor, J, Rossig, C
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2006
Fag:
Clinical Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941988/
https://ncbi.nlm.nih.gov/pubmed/16734614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03095.x
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