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Quantitative Structure-Activity Relationship (QSAR) of indoloacetamides as inhibitors of human isoprenylcysteine carboxyl methyltransferase

A QSAR is developed for the isoprenylcysteine carboxyl methyltransferase (ICMT) inhibitory activities of a series of indoloacetamides (n = 71) that are structurally related to cysmethynil, a selective ICMT inhibitor. Multivariate analytical tools (principal component analysis and projection to laten...

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書誌詳細
主要な著者: Leow, Jo-Lene, Baron, Rudi, Casey, Patrick C, Go, Mei-Lin
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941685/
https://ncbi.nlm.nih.gov/pubmed/17157012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.11.030
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