Structural Transitions and Thermodynamics of a Glycine-Dependent Riboswitch from Vibrio cholerae

Riboswitches are complex folded RNA domains found in non-coding regions of mRNA that regulate gene expression upon small molecule binding. Recently, Breaker and coworkers reported a tandem aptamer riboswitch (VCI-II) that binds glycine cooperatively. Here, we use hydroxyl radical footprinting and sm...

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Main Authors: Lipfert, Jan, Das, Rhiju, Chu, Vincent B., Kudaravalli, Madhuri, Boyd, Nathan, Herschlag, Daniel, Doniach, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941672/
https://ncbi.nlm.nih.gov/pubmed/17118400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.10.022
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