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Hyaluronan Oligosaccharides Inhibit Tumorigenicity of Osteosarcoma Cell Lines MG-63 and LM-8 in Vitro and in Vivo via Perturbation of Hyaluronan-Rich Pericellular Matrix of the Cells

Numerous studies have demonstrated a correlation between hyaluronan expression and the malignant properties of various kinds of cancer, and inhibition of hyaluronan production causes decreased tumor growth. Hyaluronan oligosaccharides have been shown to inhibit several tumor cell types via disruptio...

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Detalhes bibliográficos
Main Authors: Hosono, Kozo, Nishida, Yoshihiro, Knudson, Warren, Knudson, Cheryl B., Naruse, Takahiro, Suzuki, Yoshitaka, Ishiguro, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941604/
https://ncbi.nlm.nih.gov/pubmed/17591972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060828
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