In vivo imaging of T cell delivery to tumors after adoptive transfer therapy

Adoptive transfer therapy of in vitro-expanded tumor-specific cytolytic T lymphocytes (CTLs) can mediate objective cancer regression in patients. Yet, technical limitations hamper precise monitoring of posttherapy T cell responses. Here we show in a mouse model that fused single photon emission comp...

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Main Authors: Pittet, Mikael J., Grimm, Jan, Berger, Cedric R., Tamura, Takahiko, Wojtkiewicz, Gregory, Nahrendorf, Matthias, Romero, Pedro, Swirski, Filip K., Weissleder, Ralph
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941490/
https://ncbi.nlm.nih.gov/pubmed/17640914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704460104
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