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Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells

Recent studies have suggested that, in ES cells, inactive genes encoding early developmental regulators possess bivalent histone modification domains and are therefore poised for activation. However, bivalent domains were not observed at typical tissue-specific genes. Here, we show that windows of u...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Xu, Jian, Pope, Scott D., Jazirehi, Ali R., Attema, Joanne L., Papathanasiou, Peter, Watts, Jason A., Zaret, Kenneth S., Weissman, Irving L., Smale, Stephen T.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941477/
https://ncbi.nlm.nih.gov/pubmed/17640912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704579104
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