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Fiber-dependent amyloid formation as catalysis of an existing reaction pathway
A central component of a number of degenerative diseases is the deposition of protein as amyloid fibers. Self-assembly of amyloid occurs by a nucleation-dependent mechanism that gives rise to a characteristic sigmoidal reaction profile. The abruptness of this transition is a variable characteristic...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1941471/ https://ncbi.nlm.nih.gov/pubmed/17640888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703306104 |
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