An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5′ cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site

Eitemau Tebyg

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  Cyhoeddwyd: (2018)
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• Human Apurinic/Apyrimidinic Endonuclease 1
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• Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C
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• Polyubiquitination of Apurinic/Apyrimidinic Endonuclease 1 by Parkin
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