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Modulation of Endosomal Cholesteryl Ester Metabolism by Membrane Cholesterol

Cells acquire cholesterol in part by endocytosis of cholesteryl ester containing lipoproteins. In endosomes and lysosomes cholesteryl ester is hydrolyzed by acidic cholesteryl ester hydrolase producing cholesterol and fatty acids. Under certain pathological conditions, however, such as in atheroscle...

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Autori principali: Wang, Yan, Castoreno, Adam B., Stockinger, Walter, Nohturfft, Axel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1940112/
https://ncbi.nlm.nih.gov/pubmed/15657032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M414676200
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