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NIH 11082 produces antidepressant-like activity in the mouse tail suspension test through a delta opioid receptor mechanism of action

The present study examined the effects of NIH 11082 ((−)-(1R,5R,9R)-5,9-dimethyl-2'-hydroxy-2-(6-hydroxyhexyl)-6,7-benzomorphan hydrochloride), a benzomorphan analogue, in the mouse tail suspension, an assay used to detect antidepressant agents. NIH 11082 significantly decreased immobility time...

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Detalhes bibliográficos
Main Authors: Naidu, Pattipati S., Lichtman, Aron H., Archer, Carey C., May, Everett L., Harris, Louis S., Aceto, Mario D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939727/
https://ncbi.nlm.nih.gov/pubmed/17459369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2007.03.031
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