The DsbA Signal Sequence Directs Efficient, Cotranslational Export of Passenger Proteins to the Escherichia coli Periplasm via the Signal Recognition Particle Pathway

The Escherichia coli cytoplasmic protein thioredoxin 1 can be efficiently exported to the periplasmic space by the signal sequence of the DsbA protein (DsbAss) but not by the signal sequence of alkaline phosphatase (PhoA) or maltose binding protein (MBP). Using mutations of the signal recognition pa...

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Bibliographic Details
Main Authors: Schierle, Clark F., Berkmen, Mehmet, Huber, Damon, Kumamoto, Carol, Boyd, Dana, Beckwith, Jon
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Microbial Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC193964/
https://ncbi.nlm.nih.gov/pubmed/13129941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.19.5706-5713.2003
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