Loading...

Four cysteines of the membrane protein DsbB act in concert to oxidize its substrate DsbA

Protein disulfide bond formation in Escherichia coli is catalyzed by the periplasmic protein DsbA. A cytoplasmic membrane protein DsbB maintains DsbA in the oxidized state by transferring electrons from DsbA to quinones in the respiratory chain. Here we show that DsbB activity can be reconstituted b...

Full description

Saved in:
Bibliographic Details
Main Authors: Kadokura, Hiroshi, Beckwith, Jon
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC126001/
https://ncbi.nlm.nih.gov/pubmed/12006488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.10.2354
Tags: Add Tag
No Tags, Be the first to tag this record!