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Bur1 Kinase Is Required for Efficient Transcription Elongation by RNA Polymerase II

The Saccharomyces cerevisiae cyclin-dependent kinase (CDK) Bur1 (Sgv1) may be homologous to mammalian Cdk9, which functions in transcriptional elongation. Although Bur1 can phosphorylate the Rpb1 carboxy-terminal domain (CTD) kinase in vitro, it has no strong specificity within the consensus heptape...

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Autors principals: Keogh, Michael-Christopher, Podolny, Vladimir, Buratowski, Stephen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC193923/
https://ncbi.nlm.nih.gov/pubmed/12972617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.19.7005-7018.2003
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