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Bur1 Kinase Is Required for Efficient Transcription Elongation by RNA Polymerase II

The Saccharomyces cerevisiae cyclin-dependent kinase (CDK) Bur1 (Sgv1) may be homologous to mammalian Cdk9, which functions in transcriptional elongation. Although Bur1 can phosphorylate the Rpb1 carboxy-terminal domain (CTD) kinase in vitro, it has no strong specificity within the consensus heptape...

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Udgivet i:Mol Cell Biol
Principais autores: Keogh, Michael-Christopher, Podolny, Vladimir, Buratowski, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12972617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.19.7005-7018.2003
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