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Phosphorylation of the Carboxyl-Terminal Transactivation Domain of c-Fos by Extracellular Signal-Regulated Kinase Mediates the Transcriptional Activation of AP-1 and Cellular Transformation Induced by Platelet-Derived Growth Factor

Polypeptide growth factors, such as platelet-derived growth factor (PDGF), promote the reinitiation of DNA synthesis and cell growth through multiple intracellular signaling pathways that converge in the nucleus to regulate the activity of transcription factors, thereby controlling the expression of...

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Autors principals: Monje, Paula, Marinissen, Maria Julia, Gutkind, J. Silvio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC193921/
https://ncbi.nlm.nih.gov/pubmed/12972619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.19.7030-7043.2003
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