Fatty acid-induced β cell apoptosis: A link between obesity and diabetes

Like obese humans, Zucker diabetic fatty (ZDF) rats exhibit early β cell compensation for insulin resistance (4-fold β cell hyperplasia) followed by decompensation (>50% loss of β cells). In prediabetic and diabetic ZDF islets, apoptosis measured by DNA laddering is increased 3- and >7-fold, r...

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Detaylı Bibliyografya
Asıl Yazarlar: Shimabukuro, Michio, Zhou, Yan-Ting, Levi, Moshe, Unger, Roger H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1998
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC19389/
https://ncbi.nlm.nih.gov/pubmed/9482914
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