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Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity

The influence of the high intracellular concentration of macromolecules on cell physiology is increasingly appreciated, but its impact on system-level cellular functions remains poorly quantified. To assess its potential effect, here we develop a flux balance model of Escherichia coli cell metabolis...

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Detalhes bibliográficos
Main Authors: Beg, Q. K., Vazquez, A., Ernst, J., de Menezes, M. A., Bar-Joseph, Z., Barabási, A.-L., Oltvai, Z. N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1937523/
https://ncbi.nlm.nih.gov/pubmed/17652176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609845104
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