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Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity
The influence of the high intracellular concentration of macromolecules on cell physiology is increasingly appreciated, but its impact on system-level cellular functions remains poorly quantified. To assess its potential effect, here we develop a flux balance model of Escherichia coli cell metabolis...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1937523/ https://ncbi.nlm.nih.gov/pubmed/17652176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609845104 |
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