DNA Topoisomerase III from the Hyperthermophilic Archaeon Sulfolobus solfataricus with Specific DNA Cleavage Activity

We report the production, purification, and characterization of a type IA DNA topoisomerase, previously designated topoisomerase I, from the hyperthermophilic archaeon Sulfolobus solfataricus. The protein was capable of relaxing negatively supercoiled DNA at 75°C in the presence of Mg(2+). Mutation...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Dai, Penggao, Wang, Ying, Ye, Risheng, Chen, Liang, Huang, Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Enzymes and Proteins
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193750/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12949102/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.18.5500-5507.2003
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